35354-74-6
35354-74-6
Chemical Structure
Honokiol
Synonym(s): NSC 293100
- CAS No.: 35354-74-6
- Formula:C18H18O2
- Molecular Weight:266.33
IUPAC Name: 3',5-diallyl-[1,1'-biphenyl]-2,4'-diol
InChIKey: FVYXIJYOAGAUQK-UHFFFAOYSA-N
SMILES: OC1=C(CC=C)C=C(C2=CC(CC=C)=CC=C2O)C=C1
Biological Activity: Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules. It inhibits the activation of Akt. Honokiol can readily cross the blood brain barrier[1][2][3][4].
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Honokiol | 99.85% | Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules. It inhibits the activation of Akt. Honokiol can readily cross the blood brain barrier. | ||||||||||||||||||||
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Honokiol (Standard) | ≥98% | Honokiol (Standard) is the analytical standard of Honokiol. This product is intended for research and analytical applications. Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules. It inhibits the activation of Akt. Honokiol can readily cross the blood brain barrier. | ||||||||||||||||||||
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References
- [1]. Chang KH, et al. Honokiol-induced apoptosis and autophagy in glioblastoma multiforme cells. Oncol Lett. 2013 Nov;6(5):1435-1438. [Content Brief]
- [2]. Godugu C, et al. Honokiol nanomicellar formulation produced increased oral bioavailability and anticancer effects in triple negative breast cancer (TNBC). Colloids Surf B Biointerfaces. 2017 Jan 23;153:208-219 [Content Brief]
- [3]. Lee TY, et al. Honokiol as a specific collagen receptor glycoprotein VI antagonist on human platelets: Functional ex vivo and in vivo studies. Sci Rep. 2017 Jan 5;7:40002 [Content Brief]
- [4]. Zhai H, et al. Honokiol-induced neurite outgrowth promotion depends on activation of extracellular signal-regulated kinases (ERK1/2). Eur J Pharmacol. 2005 Jun 1;516(2):112-7. [Content Brief]
