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Schisandrin A

(Synonyms: Schizandrin-A; Wuweizisu-A; Deoxyschizandrin)
12 Cited Publications
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Based on 12 publication(s) in Google Scholar

Schisandrin A inhibits CYP3A activity with an IC50 of 6.60 μM and Ki of 5.83 μM, respectively.

For research use only. We do not sell to patients.

  • Purity: 99.89%
  • CAS No.: 61281-38-7
  • Formula: C24H32O6
  • Molecular Weight:416.51
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 2 years , -20°C, 1 year
  • Schisandrin A Chemical Structure
    Schisandrin A Chemical Structure
  • Experimental Validation Results for Schisandrin A
  • Experimental Validation Results for Schisandrin A
  • Experimental Validation Results for Schisandrin A
  • Experimental Validation Results for Schisandrin A
  • Experimental Validation Results for Schisandrin A
  • Experimental Validation Results for Schisandrin A
  • Experimental Validation Results for Schisandrin A
CAS No.: 61281-38-7
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Cell Proliferation/Viability AssayHistological Imaging/StainingIFWBFlow Cytometry
  • Cell Proliferation/Viability Assay
  • Histological Imaging/Staining
  • IF
  • WB
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  • Flow Cytometry
  • WB

All Cytochrome P450 Isoforms

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  • Schisandrin A Chemical Structure
    Schisandrin A Chemical Structure
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    Schisandrin A purchased from MedChemExpress. Usage Cited in: Cell Prolif. 2020 Oct;53(10):e12882. [Abstract]

    Customer Validation
     Representative images of TRAcP staining showing that Sch (Schisandrin A) (50-200 μM; 24-72 h) inhibited osteoclastogenesis dose‐dependently. BMMs were stimulated with M‐CSF and RANKL in the absence or presence of different concentrations of Sch.

  • 1/16

    Schisandrin A purchased from MedChemExpress. Usage Cited in: Cell Prolif. 2020 Oct;53(10):e12882. [Abstract]

    Customer Validation
     Schisandrin A (Sch) (100 mg/kg; every other day over 6 weeks). Representative images of bone cryosections showing DHE fluorescence in different groups.

  • 1/16

    Schisandrin A purchased from MedChemExpress. Usage Cited in: Cell Prolif. 2020 Oct;53(10):e12882. [Abstract]

    Customer Validation
     Schisandrin A (Sch) (100 mg/kg; every other day over 6 weeks). Immunofluorescence staining was performed to detect the expression of Nrf2. Nuclear translocations of Nrf2 were observed in the zoom pictures. Quantitative analysis of Nrf2 immunofluorescence intensity.

  • 1/16

    Schisandrin A purchased from MedChemExpress. Usage Cited in: Cell Prolif. 2020 Oct;53(10):e12882. [Abstract]

    Customer Validation
     Western Blot images of the effects of Sch on TRAF6, Nrf2, Nox1, catalase and HO‐1 expression. BMMs were stimulated by RANKL (50 ng/mL) in the absence or presence of Sch (Schisandrin A) (0, 50, 100, 200 μmol/L) for 2 d, and then, proteins were harvested for Western blot.

  • 1/16

    Schisandrin A purchased from MedChemExpress. Usage Cited in: Cell Prolif. 2020 Oct;53(10):e12882. [Abstract]

    Customer Validation
     Frequency of apoptotic cells of BMMs co‐cultured with 20 ng/mL M‐CSF and 50 ng/mL RANKL at the concentration of 200 μmol/L Sch (Schisandrin A) for 2 d (n = 3 per group).

  • 1/16

    Schisandrin A purchased from MedChemExpress. Usage Cited in: Eur J Pharmacol. 2019 Jul 15:855:10-19. [Abstract]

    Customer Validation
     HCC827GR cells were treated with Sch A (Schisandrin A) alone (20 or 40 μM), Gefi alone (15 μM) or treated with combination of Sch A (20 or 40 μM) and Gefi (15 μM) for 24 h, and the cell cycle distribution was analyzed by the cytometry (Becton Dickinson FACSCalibor, BD Biosciences, Franklin Lakes, NJ).

  • 1/16

    Schisandrin A purchased from MedChemExpress. Usage Cited in: Eur J Pharmacol. 2019 Jul 15:855:10-19. [Abstract]

    Customer Validation
     After HCC827GR cells were treated with TNF-α (10 ng/mL) with or without Sch A (Schisandrin A) (20 and 40 μM) for 2 h, NF-κB p65 levels in the nucleus and cytoplasm were determined by Western blot.

  • Schisandrin A