500-38-9
500-38-9
Chemical Structure
Nordihydroguaiaretic acid
Synonym(s): NDGA
- CAS No.: 500-38-9
- Formula:C18H22O4
- Molecular Weight:302.36
IUPAC Name: 4,4'-(2,3-dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)
InChIKey: HCZKYJDFEPMADG-UHFFFAOYSA-N
SMILES: CC(CC1=CC=C(O)C(O)=C1)C(C)CC2=CC=C(O)C(O)=C2
Biological Activity: Nordihydroguaiaretic acid is a 5-lipoxygenase (5LOX) (IC50=8 μM) and tyrosine kinase inhibitor.
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Nordihydroguaiaretic acid | 99.93% | Nordihydroguaiaretic acid is a 5-lipoxygenase (5LOX) (IC50=8 μM) and tyrosine kinase inhibitor. | ||||||||||||||||||||
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Nordihydroguaiaretic acid (Standard) | 99.86% | Nordihydroguaiaretic acid (Standard) is the analytical standard of Nordihydroguaiaretic acid. This product is intended for research and analytical applications. Nordihydroguaiaretic acid is a 5-lipoxygenase (5LOX) (IC50=8 μM) and tyrosine kinase inhibitor. | ||||||||||||||||||||
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Masoprocol | 99.30% | Masoprocol (meso-Nordihydroguaiaretic acid) is a potent and orally active lipoxygenase inhibitor. Masoprocol shows antihyperglycemic activity. Masoprocol decreases the glucose concentration and hepatic triglyceride in vivo. Masoprocol has the potential for the research of type II diabetes. | ||||||||||||||||||||
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Dihydroguaiaretic acid | Dihydroguaiaretic acid is a lignan product that can be isolated from Myristica fragrans. | |||||||||||||||||||||
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Dobutamine | 98.75% | Dobutamine is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine can increase cardiac output and correct hypoperfusion. | ||||||||||||||||||||
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Macelignan | 99.78% | Macelignan ((+)-Anwulignan; Anwuligan)?is an orally active lignan isolated from Myristica fragrans. Macelignan possesses many pharmacological activities, including anti-inflammatory, anti-cancer, anti-diabetes, and neuroprotective activities. | ||||||||||||||||||||
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(-)-Dihydroguaiaretic acid | 98.79% | (-)-Dihydroguaiaretic acid is a Lipoxygenase inhibitor that has antioxidant activity. (-)-Dihydroguaiaretic acid inhibits the oxidation of unsaturated fatty acids and removes free radicals. (-)-Dihydroguaiaretic acid also has anticancer activity with an IC50 value of 7.49 μM (A549 cells). | ||||||||||||||||||||
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erythro-Austrobailignan-6 | erythro-Austrobailignan-6 is an orally active anti-cancer agent. erythro-Austrobailignan-6 inhibits DNA topoisomerase I and II activity. erythro-Austrobailignan-6 induces cell apoptosis and increases phosphorylation of p38 and JNK. | |||||||||||||||||||||
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Rubranol | Rubranol is an inhibitor of NO Synthase. Rubranol inhibits LPS-induced NO production in activated macrophages with 74% inhibition. | |||||||||||||||||||||
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Muricarpone B | Muricarpone B is a natural product. | |||||||||||||||||||||
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Hirsutenone | 99.74% | Hirsutenone is an active botanical diarylheptanoid present in Alnus species and exhibits many biological activities, including anti-inflammatory, anti-tumor promoting and anti-atopic dermatitis effects. Hirsutenone attenuates adipogenesis by binding directly to PI3K and ERK1 in a non-ATP competitive manner. Hirsutenone can be used for the study of obesity. | ||||||||||||||||||||
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meso-Dihydroguaiaretic acid | 98.49% | Dihydroguaiaretic acid, is isolated from the fruits of Saururus chinensis with an anti-cancer activty. | ||||||||||||||||||||
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