1. Saccharides and Glycosides
    Phenylpropanoids
  2. Secoisolariciresinol diglucoside

Secoisolariciresinol diglucoside (Synonyms: (S,S)-SDG; (S,S)-LGM2605)

Cat. No.: HY-105008 Purity: 99.94%
Handling Instructions

Secoisolariciresinol diglucoside ((S,S)-SDG), the main lignan in wholegrain flaxseed, is known for its beneficial effects including anti-inflammatory, antioxidant, anti-mutagenic, anti-microbial, anti-obesity, hypolipidemic, and neuroprotective effects.

For research use only. We do not sell to patients.

Secoisolariciresinol diglucoside Chemical Structure

Secoisolariciresinol diglucoside Chemical Structure

CAS No. : 257930-74-8

Size Price Stock Quantity
10 mM * 1 mL in Water USD 145 In-stock
Estimated Time of Arrival: December 31
5 mg USD 96 In-stock
Estimated Time of Arrival: December 31
10 mg USD 168 In-stock
Estimated Time of Arrival: December 31
25 mg USD 336 In-stock
Estimated Time of Arrival: December 31
50 mg USD 468 In-stock
Estimated Time of Arrival: December 31
100 mg USD 804 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 3 publication(s) in Google Scholar

Other Forms of Secoisolariciresinol diglucoside:

Top Publications Citing Use of Products

Publications Citing Use of MCE Secoisolariciresinol diglucoside

    Secoisolariciresinol diglucoside purchased from MCE. Usage Cited in: Mediat Inflamm. 2020 Jun 24;2020:3621261.

    Representative immunoblots of cleaved caspase-3, Bcl-2, and Bax proteins in different groups.
    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    Secoisolariciresinol diglucoside ((S,S)-SDG), the main lignan in wholegrain flaxseed, is known for its beneficial effects including anti-inflammatory, antioxidant, anti-mutagenic, anti-microbial, anti-obesity, hypolipidemic, and neuroprotective effects[1][2].

    In Vitro

    Secoisolariciresinol diglucoside (1-500 μM) possesses strong reducing power and high free radical scavenging activity for hydroxyl, peroxyl and DPPH free radicals[1].
    Secoisolariciresinol diglucoside (1-50 μM; 24 h) attenuates human monocyte adhesion to and migration across human brain endothelial monolayers[2].

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.

    In Vivo

    Secoisolariciresinol diglucoside (4 mg/mouse; a single p.o.) diminishes leukocyte adhesion and migration across blood-brain barrier (BBB) in neuroinflammation[2].

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: Hand feeding mice (10 weeks old, male) are injected with TNFα[2]
    Dosage: 4 mg/mouse
    Administration: P.o. 2 h before i.c. administration of TNFα
    Result: Attenuated adhesion of leukocytes to the endothelium by 50% and attenuated migration of leukocytes across the BBB by 64%.
    Molecular Weight

    686.70

    Formula

    C₃₂H₄₆O₁₆

    CAS No.

    257930-74-8

    SMILES
    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage
    Powder -20°C 3 years
    4°C 2 years
    In solvent -80°C 6 months
    -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    H2O : ≥ 100 mg/mL (145.62 mM)

    *"≥" means soluble, but saturation unknown.

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.4562 mL 7.2812 mL 14.5624 mL
    5 mM 0.2912 mL 1.4562 mL 2.9125 mL
    10 mM 0.1456 mL 0.7281 mL 1.4562 mL
    *Please refer to the solubility information to select the appropriate solvent.
    References

    Purity: 99.94%

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    Keywords:

    Secoisolariciresinol diglucoside(S,S)-SDG (S,S)-LGM2605OthersInhibitorinhibitorinhibit

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    Product Name:
    Secoisolariciresinol diglucoside
    Cat. No.:
    HY-105008
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