1. Natural Products
  2. Disease Research Fields Plants Phenylpropanoids
  3. Araliaceae Inflammation/Immunology Lignans
  4. Acanthopanax senticosus (Rupr. et Maxim.) Harms
  5. Eleutheroside E

Eleutheroside E 

Cat. No.: HY-N0272 Purity: 98.09%
COA Handling Instructions

Eleutheroside E, a principal component of Acanthopanax senticosus, has anti-inflammatory and protective effects in ischemia heart.

For research use only. We do not sell to patients.

Eleutheroside E Chemical Structure

Eleutheroside E Chemical Structure

CAS No. : 39432-56-9

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 74 In-stock
Solution
10 mM * 1 mL in DMSO USD 74 In-stock
Solid
5 mg USD 45 In-stock
10 mg USD 70 In-stock
25 mg USD 140 In-stock
50 mg USD 210 In-stock
100 mg USD 315 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Eleutheroside E:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Eleutheroside E

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Eleutheroside E, a principal component of Acanthopanax senticosus, has anti-inflammatory and protective effects in ischemia heart. IC50 value: Target: In vitro: Treatment of 10 μM Eleutheroside E (EE) for 24 h increased basal glucose uptake as well as improved TNF-α-mediated suppression of glucose uptake. [2] In vivo: To investigate the effect of Eleutheroside E (EE) on arthritis, the CIA model in DBA/1 mice was used. Compared to vehicle-treated CIA mice, 15 mg/kg TG treatment and 30 and 60 mg/kg EE treatment obviously decreased the arthritis scores and body weight loss in CIA mice (P<0.01) [1].

Molecular Weight

742.72

Formula

C34H46O18

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC(C=C1[C@H]2[C@@](CO[C@@H]3C4=CC(OC)=C(O[C@@H]([C@@H]([C@@H](O)[C@@H]5O)O)O[C@@H]5CO)C(OC)=C4)([H])[C@]3([H])CO2)=C(C(OC)=C1)O[C@@H]([C@@H]([C@@H](O)[C@@H]6O)O)O[C@@H]6CO

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (134.64 mM; Need ultrasonic)

H2O : 1 mg/mL (1.35 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3464 mL 6.7320 mL 13.4640 mL
5 mM 0.2693 mL 1.3464 mL 2.6928 mL
10 mM 0.1346 mL 0.6732 mL 1.3464 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (3.37 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (3.37 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL (3.37 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Eleutheroside E
Cat. No.:
HY-N0272
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