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  3. Phillygenin

Phillygenin (Synonyms: Phillygenol; Epipinoresinol methyl ether; (+)-Phillygenin)

Cat. No.: HY-N0483 Purity: >98.0%
Handling Instructions

Phillygenin is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation.

For research use only. We do not sell to patients.

Phillygenin Chemical Structure

Phillygenin Chemical Structure

CAS No. : 487-39-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 132 In-stock
Estimated Time of Arrival: December 31
5 mg USD 120 In-stock
Estimated Time of Arrival: December 31
10 mg USD 180 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

Phillygenin is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation. In vitro : 1) Phillygenin shows a greater inhibition on mouse B16 melanoma cells potential than vincristine. 2) phillygenin had notable scavenging activity against DPPH, ABTS radicals, as well as potent reducing power in FRAP assay. In vivo: The reference for rat is 5.6 mg/m l ( i.v).

Molecular Weight

372.41

Formula

C₂₁H₂₄O₆

CAS No.

487-39-8

SMILES

OC1=CC=C([[email protected]]2OC[[email protected]@]3([H])[[email protected]]2([H])CO[[email protected]]3C4=CC=C(OC)C(OC)=C4)C=C1OC

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (134.26 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6852 mL 13.4261 mL 26.8521 mL
5 mM 0.5370 mL 2.6852 mL 5.3704 mL
10 mM 0.2685 mL 1.3426 mL 2.6852 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 3.25 mg/mL (8.73 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 3.25 mg/mL (8.73 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 3.25 mg/mL (8.73 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Phillygenin
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