2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species
  4. Phillygenin

Phillygenin  (Synonyms: Phillygenol; Epipinoresinol methyl ether; (+)-Phillygenin)

Cat. No.: HY-N0483 Purity: ≥98.0%
COA Handling Instructions

Phillygenin (Phillygenol) is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation.

For research use only. We do not sell to patients.

Phillygenin Chemical Structure

Phillygenin Chemical Structure

CAS No. : 487-39-8

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 132 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 132 In-stock
Solid
1 mg USD 57 In-stock
5 mg USD 120 In-stock
10 mg USD 180 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Phillygenin Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Phillygenin

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Phillygenin (Phillygenol) is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation.

In Vitro

1) Phillygenin shows a greater inhibition on mouse B16 melanoma cells potential than vincristine[1].
2) phillygenin had notable scavenging activity against DPPH, ABTS radicals, as well as potent reducing power in FRAP assay.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Phillygenin Related Antibodies
In Vivo

The reference for rat is 5.6 mg/m l ( i.v).

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

372.41

Appearance

Solid

Formula

C21H24O6
CAS No.
SMILES

OC1=CC=C([C@H]2OC[C@@]3([H])[C@]2([H])CO[C@H]3C4=CC=C(OC)C(OC)=C4)C=C1OC
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (134.26 mM; Need ultrasonic)

H2O : 0.67 mg/mL (1.80 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6852 mL 13.4261 mL 26.8521 mL
5 mM 0.5370 mL 2.6852 mL 5.3704 mL
10 mM 0.2685 mL 1.3426 mL 2.6852 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 3.25 mg/mL (8.73 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 3.25 mg/mL (8.73 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 3.25 mg/mL (8.73 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Phillygenin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Phillygenin487-39-8Phillygenol Epipinoresinol methyl ether (+)-PhillygeninReactive Oxygen SpeciesInhibitorinhibitorinhibit

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