1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. Mal-C6-α-Amanitin

Mal-C6-α-Amanitin 

Cat. No.: HY-126683
Handling Instructions

Mal-C6-α-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6.

For research use only. We do not sell to patients.

Mal-C6-α-Amanitin Chemical Structure

Mal-C6-α-Amanitin Chemical Structure

CAS No. : 1578249-76-9

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Description

Mal-C6-α-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6.

IC50 & Target[1]

Daunorubicins/Doxorubicins

 

Molecular Weight

1211.34

Formula

C₅₅H₇₈N₁₂O₁₇S

CAS No.

1578249-76-9

SMILES

O=S1C2=C(C[[email protected]]3([H])NC([[email protected]](NC([[email protected]@]4([H])N(C[[email protected]](O)C4)C([[email protected]@](CC(N)=O)([H])NC([[email protected]](NC(CNC([[email protected]@]([[email protected]@H](C)CC)([H])NC(CNC3=O)=O)=O)=O)([H])C1)=O)=O)=O)([H])[[email protected]@H](C)[[email protected]@H](O)CO)=O)C5=CC=C(OCCCCCCNC(CCCCCN6C(C=CC6=O)=O)=O)C=C5N2

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Mal-C6-α-AmanitinDrug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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Mal-C6-α-Amanitin
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