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Cat. No.: HY-151495

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CAII-IN-3

CAII-IN-3 (compound 3h), a thiosemicarbazones derivatives, is a potent carbonic anhydrase-II (CA-II) inhibitor with an IC₅₀ value of 13.4 µM.

For research use only. We do not sell to patients.

Formula: C₁₈H₁₈F₂N₄S
Molecular Weight:360.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

CAII-IN-3 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

CAII-IN-3 (compound 3h), a thiosemicarbazones derivatives, is a potent carbonic anhydrase-II (CA-II) inhibitor with an IC₅₀ value of 13.4 µM^[1].

IC₅₀ & Target^[1]

bovine CA-II

13.4 μM (IC₅₀)

All Carbonic Anhydrase Isoforms :

Chemical Information

Molecular Weight 360.42
Formula C₁₈H₁₈F₂N₄S
SMILES

FC1=CC(F)=CC=C1NC(N/N=C/C=C/C2=CC=C(C=C2)N(C)C)=S
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Rasool A, et al. Bis-pharmacophore of cinnamaldehyde-clubbed thiosemicarbazones as potent carbonic anhydrase-II inhibitors. Sci Rep. 2022 Sep 27;12(1):16095. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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CAII-IN-3

All Carbonic Anhydrase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CAII-IN-3 Related Classifications

HY-151495 Related Classifications