hCAII-IN-9
Based on 1 Customer Validation
hCAII-IN-9 is a potent carbonic anhydrase inhibitor with IC50s of 1.18 μM (hCA II), 0.17 μM (hCA IX), and 2.99 μM (hCA XII), respectively. hCAII-IN-9 has no blood-brain barrier permeability.
For research use only. We do not sell to patients.
- Purity: 98.75%
- CAS No.: 2878477-18-8
- Formula: C15H16ClN3O5S2
- Molecular Weight:417.89
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
hCA II 1.18 μM (IC50) |
hCA IX 0.17 μM (IC50) |
hCA XII 2.99 μM (IC50) |
In Vitro
hCAII-IN-9 (compound 11) (100 μM; 24-48 h) inhibits BHK-21 and HEK-293 cells with cell viability rates of 48% and 72%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2878477-18-8
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Appearance Powder
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Molecular Weight 417.89
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Formula C15H16ClN3O5S2
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SMILES
CC1=CC(C)=CC(C(NC2=CC(Cl)=C(C=C2S(N)(=O)=O)S(N)(=O)=O)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
hCAII-IN-9 Related Classifications
HY-152141 Related Classifications
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