hCAII-IN-9
hCAII-IN-9 is a potent carbonic anhydrase inhibitor with IC50s of 1.18 μM (hCA II), 0.17 μM (hCA IX), and 2.99 μM (hCA XII), respectively. hCAII-IN-9 has no blood-brain barrier permeability.
For research use only. We do not sell to patients.
- CAS No.: 2878477-18-8
- Formula: C15H16ClN3O5S2
- Molecular Weight:417.89
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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hCA II 1.18 μM (IC50) |
hCA IX 0.17 μM (IC50) |
hCA XII 2.99 μM (IC50) |
hCAII-IN-9 (compound 11) (100 μM; 24-48 h) inhibits BHK-21 and HEK-293 cells with cell viability rates of 48% and 72%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2878477-18-8
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Molecular Weight 417.89
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Formula C15H16ClN3O5S2
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SMILES
CC1=CC(C)=CC(C(NC2=CC(Cl)=C(C=C2S(N)(=O)=O)S(N)(=O)=O)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)