2. Cell Cycle/DNA Damage Apoptosis
  3. Topoisomerase Apoptosis
  4. Topoisomerase II inhibitor 7

Topoisomerase II inhibitor 7 (compound 3a) is a potent inhibitor of topoisomerase II alpha subtype, with an IC50 of 3.19 μM. Topoisomerase II inhibitor 7 can induce cell cycle arrest and apoptosis.

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Topoisomerase II inhibitor 7 Chemical Structure

Topoisomerase II inhibitor 7 Chemical Structure

CAS No. : 2697171-03-0

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Topoisomerase II inhibitor 7 Related Antibodies

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Description

Topoisomerase II inhibitor 7 (compound 3a) is a potent inhibitor of topoisomerase II alpha subtype, with an IC50 of 3.19 μM. Topoisomerase II inhibitor 7 can induce cell cycle arrest and apoptosis[1].

IC50 & Target[1]

topoisomerase II alpha

3.19 μM (IC50)

Molecular Weight

674.56

Formula

C32H28BrN5O5S
CAS No.
SMILES

O=C(C1=C(C2=CC=CC=C2)N=C3SC4=C(N3C1C5=CC(OC)=C(C(OC)=C5)OC)N=C(N)N=C4C6=CC=C(Br)C=C6)OCC
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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Topoisomerase II inhibitor 7 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Topoisomerase II inhibitor 72697171-03-0Topoisomerase II inhibitor7Topoisomerase II inhibitor-7TopoisomeraseApoptosiscell cycle arrestapoptosisInhibitorinhibitorinhibit

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