2697171-03-0
Chemical Structure
Topoisomerase II inhibitor 7
- CAS No.: 2697171-03-0
- Formula:C32H28BrN5O5S
- Molecular Weight:674.56
IUPAC Name: ethyl 2-amino-4-(4-bromophenyl)-7-phenyl-9-(3,4,5-trimethoxyphenyl)-9H-thiazolo[3,2-a:4,5-d']dipyrimidine-8-carboxylate
InChIKey: ZGQOCYHQFHUDGY-UHFFFAOYSA-N
SMILES: O=C(C1=C(C2=CC=CC=C2)N=C3SC4=C(N3C1C5=CC(OC)=C(C(OC)=C5)OC)N=C(N)N=C4C6=CC=C(Br)C=C6)OCC
Biological Activity: Topoisomerase II inhibitor 7 (compound 3a) is a potent inhibitor of topoisomerase II alpha subtype, with an IC50 of 3.19 μM. Topoisomerase II inhibitor 7 can induce cell cycle arrest and apoptosis[1].
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Topoisomerase II inhibitor 7 | Topoisomerase II inhibitor 7 (compound 3a) is a potent inhibitor of topoisomerase II alpha subtype, with an IC50 of 3.19 μM. Topoisomerase II inhibitor 7 can induce cell cycle arrest and apoptosis. | |||||||||||||||||||||
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Keywords