HG-7-86-01
Based on 1 Customer Validation
HG-7-86-01 (Compound 26) is type II tyrosine kinase inhibitor. HG-7-86-01 has anti-proliferative activity.
For research use only. We do not sell to patients.
- Purity: 98.41%
- CAS No.: 1258391-14-8
- Formula: C28H21F3N6O2S
- Molecular Weight:562.57
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Immunology/Inflammation Compound Library
HY-L007
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Kinase Inhibitor Library
HY-L009
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Protein Tyrosine Kinase Compound Library
HY-L016
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Anti-Cancer Compound Library
HY-L025
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Cytoskeleton Compound Library
HY-L060
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Anti-Alzheimer's Disease Compound Library
HY-L069
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Anti-Blood Cancer Compound Library
HY-L079
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Anti-Parkinson's Disease Compound Library
HY-L085
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Neurodegenerative Disease-related Compound Library
HY-L086
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Anti-Hematopathy Compound Library
HY-L171
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MCE Bioactive Compound Library
HY-L001V
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Protein Kinase Compound Library
HY-L196
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High-Throughput Bioactive Compound Library
HY-L205
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Posttranslational Modification Library
HY-L226
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BaF3 | EC50 |
0.19 μM
Compound: 26, HG-7-86-01
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Cytotoxicity against mouse BA/F3 cells expressing imatinib resistant Bcr-Abl T3151 mutant
Cytotoxicity against mouse BA/F3 cells expressing imatinib resistant Bcr-Abl T3151 mutant
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[PMID: 22819762] |
| BaF3 | EC50 |
0.38 μM
Compound: 26, HG-7-86-01
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Cytotoxicity against mouse BA/F3 cells expressing wild type Bcr-Abl
Cytotoxicity against mouse BA/F3 cells expressing wild type Bcr-Abl
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[PMID: 22819762] |
| BaF3 | EC50 |
1.99 μM
Compound: 26, HG-7-86-01
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Cytotoxicity against wild type mouse BA/F3 cells
Cytotoxicity against wild type mouse BA/F3 cells
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[PMID: 22819762] |
Chemical Information
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CAS No. 1258391-14-8
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Appearance Solid
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Molecular Weight 562.57
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Formula C28H21F3N6O2S
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Color White to off-white
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SMILES
O=C(C1CC1)NC2=NC3=CC=C(C4=CC=CC(C(NC5=CC(N6C=NC(C)=C6)=CC(C(F)(F)F)=C5)=O)=C4)N=C3S2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 5 mg/mL (8.89 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7776 mL | 8.8878 mL | 17.7756 mL | 44.4389 mL |
| 5 mM | 0.3555 mL | 1.7776 mL | 3.5551 mL | 8.8878 mL |
HG-7-86-01 Related Classifications
HY-161057 Related Classifications
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