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  4. CALCB Protein, Human (93a.a, HEK293, Fc)

CALCB Protein, Human (93a.a, HEK293, Fc)

Cat. No.: HY-P7706
Handling Instructions

CALCB Protein, Human (93a.a, HEK293, Fc), a recombinant human Calcitonin Gene-related Peptide 2 produced in HEK293 cells, has an Fc fragment at the C-terminus. Calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide, is a highly potent vasodilator[1].

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
10 μg $60 In-stock
Estimated Time of Arrival: December 31
50 μg $180 In-stock
Estimated Time of Arrival: December 31
100 μg   Get quote  
250 μg   Get quote  

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CALCB Protein, Human (93a.a, HEK293, Fc) Related Classifications

  • Technical Parameters

  • Properties

  • Documentation

Species

Human

Source

HEK 293

Accession

P10092 (A26-F118)

Gene ID

797

Synonyms
rHuCALC2, C-Fc; Calcitonin gene-related peptide 2; Calcitonin gene-related peptide II; CALCB
AA Sequence

APFRSALESSPDPATLSKEDARLLLAALVQDYVQMKASELKQEQETQGSSSAAQKRACNTATCVTHRLAGLLSRSGGMVKSNFVPTNVGSKAF-Fctag

Molecular Weight

38-42 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Biological Activity
Data is not available.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O or PBS.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

Calcitonin gene-related peptide (CGRP) has two major forms (α and β). It belongs to a group of peptides that all act on an unusual receptor family. These receptors consist of calcitonin receptor-like receptor (CLR) linked to an essential receptor activity modifying protein (RAMP) that is necessary for full functionality. CGRP is a highly potent vasodilator and, partly as a consequence, possesses protective mechanisms that are important for physiological and pathological conditions involving the cardiovascular system and wound healing[1].

Documentation
References
  • Reconstitution Calculator

  • Dilution Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
CALCB Protein, Human (93a.a, HEK293, Fc)
Cat. No.:
HY-P7706
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