1. Cell Cycle/DNA Damage
  2. CDK
  3. 5,6-Dichlorobenzimidazole riboside

5,6-Dichlorobenzimidazole riboside (Synonyms: DRB)

Cat. No.: HY-14392 Purity: 99.87%
Handling Instructions

5,6-Dichlorobenzimidazole riboside is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II and CDKs. 5,6-Dichlorobenzimidazole riboside trigger p53-dependent apoptosis of human colon adenocarcinoma cells without inducing genotoxic stress to healthy cells.

For research use only. We do not sell to patients.

5,6-Dichlorobenzimidazole riboside Chemical Structure

5,6-Dichlorobenzimidazole riboside Chemical Structure

CAS No. : 53-85-0

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25 mg USD 90 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

5,6-Dichlorobenzimidazole riboside is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II and CDKs[1][2][3][4]. 5,6-Dichlorobenzimidazole riboside trigger p53-dependent apoptosis of human colon adenocarcinoma cells without inducing genotoxic stress to healthy cells[5].

Molecular Weight

319.14

Formula

C12H12Cl2N2O4

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : 100 mg/mL (313.34 mM; Need ultrasonic)

Ethanol : 7.69 mg/mL (24.10 mM; Need ultrasonic)

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1334 mL 15.6671 mL 31.3342 mL
5 mM 0.6267 mL 3.1334 mL 6.2668 mL
10 mM 0.3133 mL 1.5667 mL 3.1334 mL
*Please refer to the solubility information to select the appropriate solvent.
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Product Name:
5,6-Dichlorobenzimidazole riboside
Cat. No.:
HY-14392
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