1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. MC-VC-PABC-C6-alpha-Amanitin

MC-VC-PABC-C6-alpha-Amanitin 

Cat. No.: HY-131089
Handling Instructions

MC-VC-PABC-C6-alpha-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-tumor agent, alpha-Amanitin, linked via the cleavable linker MC-VC-PABC-C6.

For research use only. We do not sell to patients.

MC-VC-PABC-C6-alpha-Amanitin Chemical Structure

MC-VC-PABC-C6-alpha-Amanitin Chemical Structure

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • Customer Review

Description

MC-VC-PABC-C6-alpha-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-tumor agent, alpha-Amanitin, linked via the cleavable linker MC-VC-PABC-C6.

IC50 & Target

Daunorubicins/Doxorubicins

 

Molecular Weight

1616.79

Formula

C₇₄H₁₀₅N₁₇O₂₂S

SMILES

O=S(C[[email protected]@](NC(CNC([[email protected]@]([[email protected]@H](C)CC)([H])N1)=O)=O)([H])C(N[[email protected]@](C(N(C[[email protected]](O)C2)[[email protected]]2([H])C3=O)=O)([H])CC(N)=O)=O)C4=C(C[[email protected]](C(NCC1=O)=O)([H])NC([[email protected]](N3)([H])[[email protected]@H](C)[[email protected]@H](O)CO)=O)C5=CC=C(OCCCCCCNC(OCC6=CC=C(NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(CCCCCN7C(C=CC7=O)=O)=O)=O)=O)C=C6)=O)C=C5N4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

MC-VC-PABC-C6-alpha-AmanitinDrug-Linker Conjugates for ADCInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
MC-VC-PABC-C6-alpha-Amanitin
Cat. No.:
HY-131089
Quantity:
MCE Japan Authorized Agent: