1. Immunology/Inflammation
    Metabolic Enzyme/Protease
  2. Arginase
  3. BEC hydrochloride

BEC hydrochloride 

Cat. No.: HY-19548A Purity: >98.0%
Handling Instructions

BEC hydrochloride is a slow-binding and competitive Arginase II inhibitor with Ki of 0.31 μM (ph 7.5).

For research use only. We do not sell to patients.

BEC hydrochloride Chemical Structure

BEC hydrochloride Chemical Structure

CAS No. : 222638-67-7

Size Price Stock Quantity
10 mM * 1 mL in Water USD 121 In-stock
Estimated Time of Arrival: December 31
5 mg USD 110 In-stock
Estimated Time of Arrival: December 31
10 mg USD 190 In-stock
Estimated Time of Arrival: December 31
25 mg USD 370 In-stock
Estimated Time of Arrival: December 31
50 mg USD 680 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

BEC hydrochloride is a slow-binding and competitive Arginase II inhibitor with Ki of 0.31 μM (ph 7.5). target: Arginase II [1]; In vitro: BEC hydrochloride causes significant enhancement of NO-dependent smooth muscle relaxation in this tissue. [2] BEC hydrochloride enhances perivascular and peribronchiolar lung inflammation, mucus metaplasia, NF-κB DNA binding, and mRNA expression of the NF-κB-driven chemokine genes CCL20 and KC, and lead to further increases in airways hyperresponsiveness. [3] In vivo: BEC hydrochloride increased contractility in isolated myocytes from WT and NOS3 but not NOS1 knockout mice. [4]

Molecular Weight

229.49

Formula

C₅H₁₃BClNO₄S

CAS No.

222638-67-7

SMILES

N[[email protected]@H](CSCCB(O)O)C(O)=O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 35 mg/mL (152.51 mM)

*"≥" means soluble, but saturation unknown.

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3575 mL 21.7874 mL 43.5749 mL
5 mM 0.8715 mL 4.3575 mL 8.7150 mL
10 mM 0.4357 mL 2.1787 mL 4.3575 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
BEC hydrochloride
Cat. No.:
HY-19548A
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