Losartan-d4
Based on 1 Customer Validation
Losartan-d4 is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
For research use only. We do not sell to patients.
- Purity: 99.42%
- CAS No.: 1030937-27-9
- Formula: C22H19D4ClN6O
- Molecular Weight:426.94
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All Angiotensin Receptor Isoforms
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Biological Activity
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AT1 Receptor |
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1030937-27-9
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Unlabeled Cas 114798-26-4
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Appearance Solid
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Molecular Weight 426.94
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Formula C22H19D4ClN6O
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Color White to off-white
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SMILES
OCC1=C(Cl)N=C(CCCC)N1CC2=C([2H])C([2H])=C(C3=CC=CC=C3C4=NNN=N4)C([2H])=C2[2H]
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Synonyms
DuP-753 d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
Ethanol : ≥ 42.69 mg/mL (99.99 mM)
DMSO : ≥ 42.69 mg/mL (99.99 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (250 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMSO | 1 mM | 2.3422 mL | 11.7112 mL | 23.4225 mL | 58.5562 mL |
| 5 mM | 0.4684 mL | 2.3422 mL | 4.6845 mL | 11.7112 mL | |
| 10 mM | 0.2342 mL | 1.1711 mL | 2.3422 mL | 5.8556 mL | |
| 15 mM | 0.1561 mL | 0.7807 mL | 1.5615 mL | 3.9037 mL | |
| 20 mM | 0.1171 mL | 0.5856 mL | 1.1711 mL | 2.9278 mL | |
| 25 mM | 0.0937 mL | 0.4684 mL | 0.9369 mL | 2.3422 mL | |
| 30 mM | 0.0781 mL | 0.3904 mL | 0.7807 mL | 1.9519 mL | |
| 40 mM | 0.0586 mL | 0.2928 mL | 0.5856 mL | 1.4639 mL | |
| 50 mM | 0.0468 mL | 0.2342 mL | 0.4684 mL | 1.1711 mL | |
| 60 mM | 0.0390 mL | 0.1952 mL | 0.3904 mL | 0.9759 mL | |
| 80 mM | 0.0293 mL | 0.1464 mL | 0.2928 mL | 0.7320 mL |
Losartan-d4 Related Classifications
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