Atecegatran metoxil
Atecegatran metoxil is a oral anticoagulant, which inhibits thrombin factor II and is used in thromboembolic disorders. In vivo, Atecegatran metoxil is converted to AR-H067637, a selective and reversible direct thrombin inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 433937-93-0
- Formula: C22H23ClF2N4O5
- Molecular Weight:496.89
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 433937-93-0
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Molecular Weight 496.89
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Formula C22H23ClF2N4O5
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SMILES
O=C([C@H](O)C1=CC(OC(F)F)=CC(Cl)=C1)N(CC2)[C@@H]2C(NCC3=CC=C(C=C3)C(NOC)=N)=O
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Synonyms
AZD0837; Atecegatran fexenetil
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Lip GY, Rasmussen LH, Olsson SB, et al. Oral direct thrombin inhibitor AZD0837 for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation: a randomized dose-guiding, safety, and tolerability study of four doses of [Content Brief]
[2]. Olsson SB, Rasmussen LH, Tveit A, et al. Safety and tolerability of an immediate-release formulation of theoral direct thrombin inhibitor AZD0837 in the prevention of stroke and systemic embolism in patients with atrial fibrillation. Thromb Haemost. 2010; [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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