1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Doxorubicinone

Doxorubicinone  (Synonyms: Adriamycin aglycone; Adriamycinone)

Cat. No.: HY-121309
Handling Instructions

Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.

For research use only. We do not sell to patients.

Doxorubicinone Chemical Structure

Doxorubicinone Chemical Structure

CAS No. : 24385-10-2

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Description

Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin[1]. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.

Molecular Weight

414.36

Formula

C21H18O9

CAS No.
SMILES

OC1=C(C2=C(C(C3=O)=C1C(C4=CC=CC(OC)=C34)=O)O)C[C@](O)(C[C@@H]2O)C(CO)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Doxorubicinone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Doxorubicinone
Cat. No.:
HY-121309
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