Angiotensin-converting enzyme
Based on 1 Customer Validation
Angiotensin-converting enzyme (Kininase II) is a dicarboxypeptidase, it converts inactive Angiotensin I (Ang I) to active Ang II and degrades active bradykinin (BK). Angiotensin-converting enzyme is a potent vasoconstrictor, is often used in biochemical studies.
For research use only. We do not sell to patients.
- CAS No.: 9015-82-1
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
More
Biological Activity
Instructions
Soluble in water (1 mg/mL). Or dissolve as per specific experimental reference.
A concentration of 1 mg/ml in 0.01 M potassium phosphate buffer, pH 7.0, containing 0.5 M NaCl has been reported to remain fully active after storage at -20°C for several months. Solutions with lower concentrations are less stable.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
3.4.15.1
≥10 U/g soild
One unit is defined as the amount of enzyme that can produce 1.0 μmol Hippuric acid per minute in 50 mM HEPES and 300 mM NaCl solution at pH 8.3 and 37°C.
Chemical Information
-
CAS No. 9015-82-1
-
Appearance Solid
-
Color Off-white to light yellow
-
SMILES
[Angiotensin-converting enzyme]
-
Synonyms
Kininase II; CD143
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
-
Data Sheet (263 KB)
-
SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)