1. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  2. Nucleoside Antimetabolite/Analog
    DNA/RNA Synthesis
    Endogenous Metabolite
  3. 3'-Deoxyuridine-5'-triphosphate trisodium

3'-Deoxyuridine-5'-triphosphate trisodium (Synonyms: 3'-dUTP trisodium)

Cat. No.: HY-135780A Purity: 99.69%
Handling Instructions

3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM.

For research use only. We do not sell to patients.

3'-Deoxyuridine-5'-triphosphate trisodium Chemical Structure

3'-Deoxyuridine-5'-triphosphate trisodium Chemical Structure

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1 mg USD 1600 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

Other Forms of 3'-Deoxyuridine-5'-triphosphate trisodium:

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Description

3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1].

In Vitro

3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is synthesized starting from cordycepin in good yield. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA by the RNA polymerases. 3'-Deoxyuridine-5'-triphosphate will be useful in studies at the molecular level on the relationship of template and substrate in RNA synthesis with chromatin, isolated nuclei or permeable cells, because it does not have any effect on poly (rA) synthesis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

537.11

Formula

C9H15N2Na3O14P3

SMILES

O[[email protected]@H]([[email protected]](N1C(NC(C=C1)=O)=O)O2)C[[email protected]]2COP(O)(OP(O)(OP(O)(O)=O)=O)=O.[3].[Na]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 20 mg/mL (37.24 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8618 mL 9.3091 mL 18.6182 mL
5 mM 0.3724 mL 1.8618 mL 3.7236 mL
10 mM 0.1862 mL 0.9309 mL 1.8618 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 99.69%

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Product Name:
3'-Deoxyuridine-5'-triphosphate trisodium
Cat. No.:
HY-135780A
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