hCAI/II-IN-3
hCAI/II-IN-3 (compound 5b) is a potent dual hCA I/II inhibitor with Ki values of 51.25, 13.15 and 42.18 nM for hCA I, hCA II and hCA Ⅸ. hCAI/II-IN-3 possesses anti-hypoxic activity against acute mountain sickness (AMS) and low cellular activity.
For research use only. We do not sell to patients.
- CAS No.: 2480283-93-8
- Formula: C16H18N4O4S2
- Molecular Weight:394.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
hCAI/II-IN-3 (compound 5b) (5-200 μM, 48 hours; HEK293T cells) has no obvious toxicity at HEK293T cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Embryonic kidney (HEK293T) cells
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Concentration:5, 25, 50, 100 and 200 μM
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Incubation Time:48 hours
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Result:Had no apparent cytotoxicity.
Chemical Information
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CAS No. 2480283-93-8
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Molecular Weight 394.47
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Formula C16H18N4O4S2
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SMILES
O=C(C1=CSC(NC(C2=CC=C(S(=O)(N)=O)C=C2)=O)=N1)NC3CCCC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
hCAI/II-IN-3 Related Classifications
HY-147923 Related Classifications
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