1. Protein Tyrosine Kinase/RTK
  2. Ephrin Receptor
  3. ALW-II-49-7


Cat. No.: HY-18833
Handling Instructions

ALW-II-49-7 is a selective EphB2 kinase inhibitor with an EC50 value of 40 nM in cell.

For research use only. We do not sell to patients.

ALW-II-49-7 Chemical Structure

ALW-II-49-7 Chemical Structure

CAS No. : 1135219-23-6

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ALW-II-49-7 is a selective EphB2 kinase inhibitor with an EC50 value of 40 nM in cell[1].

IC50 & Target


In Vitro

ALW-II-49-7 (compound 9) exhibits selectivity profile of binding to a set of kinases including b-raf, CSF1R, DDR1, DDR2, EphA2, EphA5, EphA8, EphB1, EphB2, EphB3, Frk, Kit, Lck, p38a, p38b, PDGFRa, PDGFRb, and Raf1[1].
ALW-II-49-7 (0.01-10 μM; 1 h) inhibits EphB2 tyrosine kinase activity in U87 glioblastoma cells. EphB2 is added in media at 2 μg/mL[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight







Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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