EphA5
EphA5, also called ECK, EPH-2 or Tyro4, is an EphA receptor with prominent expression in the developing and adult nervous system as well as in lung and testis. Interactions with ephrin-A ligands regulate axon guidance, dendritic spine morphology and hippocampal-dependent synaptic plasticity, and EphA5 signaling has been linked to reward-related behavior and addiction circuitry. In oncology, elevated EphA5 expression has been reported in prostate and lung cancers, where it may drive migration and invasion. Recombinant EphA5 extracellular domain reagents facilitate ephrin-A binding analyses and studies of Eph-ephrin bidirectional signaling in neural and tumor contexts.
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EphA5 Recombinant Proteins (5)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
