1. GPCR/G Protein
  2. Ras
  3. ARS-1323-alkyne

ARS-1323-alkyne 

Cat. No.: HY-128522
Handling Instructions

ARS-1323-alkyne, a switch-II pocket (S-IIP) inhibitor, is a conformational specific chemical reporter of KRASG12C nucleotide state in living cells.

For research use only. We do not sell to patients.

ARS-1323-alkyne Chemical Structure

ARS-1323-alkyne Chemical Structure

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Description

ARS-1323-alkyne, a switch-II pocket (S-IIP) inhibitor, is a conformational specific chemical reporter of KRASG12C nucleotide state in living cells[1].

IC50 & Target

Switch-II pocket[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

569.00

Formula

C₂₈H₂₇ClF₂N₆O₃

SMILES

O=C(C=C)N1CCN(C2=NC(NCCC(N(C)CC#C)=O)=NC3=C(F)C(C4=C(O)C=CC=C4F)=C(Cl)C=C23)CC1

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
ARS-1323-alkyne
Cat. No.:
HY-128522
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ARS-1323-alkyne

Cat. No.: HY-128522