UIAA-II-232
UIAA-II-232 (compound 19b) is a potent DNA gyrase catalytic inhibitor with an IC50 value of 3.5 µM.
For research use only. We do not sell to patients.
- CAS No.: 2428407-03-6
- Formula: C20H24FN5O3
- Molecular Weight:401.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Description
IC50 & Target
IC50: 3.5 µM (DNA gyrase catalytic)[1].
Chemical Information
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CAS No. 2428407-03-6
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Molecular Weight 401.43
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Formula C20H24FN5O3
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SMILES
O=C(C1=C2N(N=C1)C(N(CC)C3=C2C=C(F)C(N4C[C@H](CN)CC4)=C3)=O)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)