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Cat. No.: HY-147729

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UIAA-II-232

UIAA-II-232 (compound 19b) is a potent DNA gyrase catalytic inhibitor with an IC₅₀ value of 3.5 µM.

For research use only. We do not sell to patients.

CAS No.: 2428407-03-6
Formula: C₂₀H₂₄FN₅O₃
Molecular Weight:401.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

UIAA-II-232 Chemical Structure

CAS No.: 2428407-03-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

UIAA-II-232 (compound 19b) is a potent DNA gyrase catalytic inhibitor with an IC₅₀ value of 3.5 µM^[1].

IC₅₀ & Target

IC₅₀: 3.5 µM (DNA gyrase catalytic)^[1].

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 2428407-03-6
Molecular Weight 401.43
Formula C₂₀H₂₄FN₅O₃
SMILES

O=C(C1=C2N(N=C1)C(N(CC)C3=C2C=C(F)C(N4C[C@H](CN)CC4)=C3)=O)OCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Aguirre AL, et al. Identification of an ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate as a catalytic inhibitor of DNA gyrase. Bioorg Med Chem. 2020 May 15;28(10):115439. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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UIAA-II-232

All DNA/RNA Synthesis Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

UIAA-II-232 Related Classifications

HY-147729 Related Classifications