2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Batracylin

Batracylin  (Synonyms: NSC 320846; BAY-H 2049)

Cat. No.: HY-119892
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Batracylin (NSC320846) is a potent DNA Topoisomerases I and DNA Topoisomerases II inhibitor. Batracylin shows cytotoxicity and antiproliferative activity. Batracylin induces DNA breaks.

For research use only. We do not sell to patients.

Batracylin Chemical Structure

Batracylin Chemical Structure

CAS No. : 67199-66-0

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Batracylin Related Antibodies

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Description

Batracylin (NSC320846) is a potent DNA Topoisomerases I and DNA Topoisomerases II inhibitor. Batracylin shows cytotoxicity and antiproliferative activity. Batracylin induces DNA breaks[1].

In Vitro

Batracylin (0-300 µM; 6 h) shows cytotoxicity with an IC50 value of 10.02 µM for HT29 cells[1].
Batracylin (100, 300 µM; 3 h) induces protein-linked DNA breaks consistent with topoisomerase targeting[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Batracylin Related Antibodies
Clinical Trial
Molecular Weight

249.27

Formula

C15H11N3O
CAS No.
SMILES

O=C1C2=C(C=CC=C2)C3=NC4=C(CN31)C=C(C=C4)N
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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Batracylin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Batracylin67199-66-0NSC 320846 BAY-H 2049NSC320846NSC-320846TopoisomeraseHT29 cellsDNA breaksγ-H2AXcytotoxicityInhibitorinhibitorinhibit

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