1. Neuronal Signaling
  2. CaMK

Autocamtide 2 (Synonyms: Autocamtide II; Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu; KKALRRQETVDAL)

Cat. No.: HY-P0225 Purity: 98.17%
Handling Instructions

Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay.

For research use only. We do not sell to patients.
Autocamtide 2 Chemical Structure

Autocamtide 2 Chemical Structure

CAS No. : 129198-88-5

Size Price Stock Quantity
10 mM * 1 mL in Water USD 1452 In-stock
1 mg USD 108 In-stock
5 mg USD 432 In-stock
10 mg   Get quote  
50 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References


Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay.

In Vitro

The Ca/calmodulin dependent protein kinases (CaMKs) are multifunctional serine/threonine kinases whose activity are regulated through Ca2+ signaling. It is multifunctional best known for its critical role in learning and memory. Recent studies demonstrates that high levels of different isoform of CaMK, especially for CaMKII, expresses in several cancers such as lung, breast, prostate and colon cancer. CaMKII phosphorylates nearly 40 different proteins, including enzymes, ion channels, kinases, and transcription factors and plays a critical role in the regulation of proliferation, differentiation and survival of various cancer cells[1].

Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 0.6545 mL 3.2727 mL 6.5455 mL
5 mM 0.1309 mL 0.6545 mL 1.3091 mL
10 mM 0.0655 mL 0.3273 mL 0.6545 mL
Please refer to the solubility information to select the appropriate solvent.
Molecular Weight







O=C(N[[email protected]@H](CCC(N)=O)C(N[[email protected]@H](CCC(O)=O)C(N[[email protected]@H]([[email protected]](O)C)C(N[[email protected]@H](C(C)C)C(N[[email protected]@H](CC(O)=O)C(N[[email protected]@H](C)C(N[[email protected]](C(O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)[[email protected]](CCCNC(N)=N)NC([[email protected]](CCCNC(N)=N)NC([[email protected]](CC(C)C)NC([[email protected]](C)NC([[email protected]](CCCCN)NC([[email protected]@H](N)CCCCN)=O)=O)=O)=O)=O

Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month

Room temperature in continental US; may vary elsewhere

Solvent & Solubility


* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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