1. Neuronal Signaling
  2. CaMK

Autocamtide 2 (Synonyms: Autocamtide II)

Cat. No.: HY-P0225 Purity: 98.17%
Handling Instructions

Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay. Sequence: Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Autocamtide 2 Chemical Structure

Autocamtide 2 Chemical Structure

CAS No. : 129198-88-5

Size Price Stock Quantity
1 mg USD 108 In-stock
Estimated Time of Arrival: December 31
5 mg USD 432 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay. Sequence: Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu.

In Vitro

The Ca/calmodulin dependent protein kinases (CaMKs) are multifunctional serine/threonine kinases whose activity are regulated through Ca2+ signaling. It is multifunctional best known for its critical role in learning and memory. Recent studies demonstrates that high levels of different isoform of CaMK, especially for CaMKII, expresses in several cancers such as lung, breast, prostate and colon cancer. CaMKII phosphorylates nearly 40 different proteins, including enzymes, ion channels, kinases, and transcription factors and plays a critical role in the regulation of proliferation, differentiation and survival of various cancer cells[1].

Solvent & Solubility
In Vitro: 

10 mM in H2O

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6545 mL 3.2727 mL 6.5455 mL
5 mM 0.1309 mL 0.6545 mL 1.3091 mL
10 mM 0.0655 mL 0.3273 mL 0.6545 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

1527.77

Formula

C₆₅H₁₁₈N₂₂O₂₀

CAS No.

129198-88-5

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
Autocamtide 2
Cat. No.:
HY-P0225
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Autocamtide 2

Cat. No.: HY-P0225