1. Cell Cycle/DNA Damage Anti-infection
  2. Topoisomerase Bacterial
  3. Murrayanol

Murrayanol is a natural carbazole alkaloid with a variety of biological activities. Murrayanol shows anti-inflammatory, topoisomerase I and topoisomerase II (Topoisomerase) inhibition activities. Murrayanol also as a mosquitocidal and antimicrobial.

For research use only. We do not sell to patients.

Murrayanol Chemical Structure

Murrayanol Chemical Structure

CAS No. : 144525-81-5

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Description

Murrayanol is a natural carbazole alkaloid with a variety of biological activities. Murrayanol shows anti-inflammatory, topoisomerase I and topoisomerase II (Topoisomerase) inhibition activities. Murrayanol also as a mosquitocidal and antimicrobial[1].

In Vitro

Murrayanol (Compound 2) shows an IC50 of 109 μg/mL against human prostaglandin H synthase isozyme 1 (hPGHS-1) and an IC50 of 218 μg/mL against hPGHS-2 in anti-inflammatory assays[1].
Murrayanol (Compound 2) shows 100% mortality at 12.5 µg/mL concentrations for Aedes aegyptii[1].
Murrayanol (Compound 2) completely inhibits topoisomerase I and II activity at 50 µg/mL concentrations when tested on S. cerevisiae mutant strains[1].
Murrayanol (Compound 2) shows an MIC100 of 100 µg/mL against C. kruseii and E. coli but give an MIC100 against S. aureus and S. pyogenes at 25 µg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

363.49

Formula

C24H29NO2

CAS No.
SMILES

OC1=C(C/C=C(C)/CC/C=C(C)\C)C(NC2=C3C=C(C)C(OC)=C2)=C3C=C1

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Murrayanol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Murrayanol
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HY-116933
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