Collagen Type II Fragment

Name: Collagen Type II Fragment
Brand: MedChemExpress
SKU: HY-P5003
Rating: 4.5 (1 reviews)

Cat. No.: HY-P5003 Purity: 99.39%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Collagen Type II Fragment is an anti-inflammatory peptide that potently inhibits collagen-induced arthritis (CIA) in mice. Collagen Type II Fragment can be used for research on inflammation and immunity.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Collagen Type II Fragment Chemical Structure

CAS No. : 144703-90-2

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

2488.71

Formula

C₁₀₆H₁₇₄N₃₂O₃₇

CAS No.

144703-90-2

Appearance

Solid

Color

White to off-white

Sequence

Pro-Thr-Gly-Pro-Leu-Gly-Pro-Lys-Gly-Gln-Thr-Gly-Glu-Leu-Gly-Ala-{Hyp}-Gly-Asn-Lys-Gly-Glu-Gln-Gly-Pro-Lys

Sequence Shortening

PTGPLGPKGQTGELGA-{Hyp}-GNKGEQGPK

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (40.18 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.4018 mL	2.0091 mL	4.0181 mL
5 mM	0.0804 mL	0.4018 mL	0.8036 mL
10 mM	0.0402 mL	0.2009 mL	0.4018 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.39%

Select Batch:

Data Sheet (267 KB) SDS (252 KB)

COA (242 KB) RP-HPLC (111 KB) MS (179 KB) Elemental Analysis Report (100 KB)

Handling Instructions (2659 KB)

References

[1]. Myers LK, et al. Characterization of a peptide analog of a determinant of type II collagen that suppresses collagen-induced arthritis. J Immunol. 1998 Oct 1;161(7):3589-95. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.4018 mL	2.0091 mL	4.0181 mL	10.0454 mL
	5 mM	0.0804 mL	0.4018 mL	0.8036 mL	2.0091 mL
	10 mM	0.0402 mL	0.2009 mL	0.4018 mL	1.0045 mL
	15 mM	0.0268 mL	0.1339 mL	0.2679 mL	0.6697 mL
	20 mM	0.0201 mL	0.1005 mL	0.2009 mL	0.5023 mL
	25 mM	0.0161 mL	0.0804 mL	0.1607 mL	0.4018 mL
	30 mM	0.0134 mL	0.0670 mL	0.1339 mL	0.3348 mL
	40 mM	0.0100 mL	0.0502 mL	0.1005 mL	0.2511 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.