vMIP-II (1-21)
vMIP-II (1-21) (NT21MP) is an inhibitor of CXCR4. vMIP-II (1-21) interacts broadly with CC and CXC chemokine receptors. vMIP-II (1-21) inhibits CXCR4 by competing with 125I-SDF-1R for binding sites (IC50=190 nM).
For research use only. We do not sell to patients.
- CAS No.: 265650-93-9
- Formula: C108H169N33O27S
- Molecular Weight:2425.84
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
vMIP-II (1-21) (0.01-10 μM) binds with CXCR4[1]. vMIP-II (1-21) (25-200 μM) inhibits CXCR4 mediates T- and dual-tropic HIV-1 gp120-mediated cell-cell fusion[1]. vMIP-II (1-21) (100 μM) dose-dependently inhibits the chemotactic activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 265650-93-9
-
Molecular Weight 2425.84
-
Formula C108H169N33O27S
-
Synonyms
NT21MP; V1 peptide
-
Sequence
Leu-Gly-Ala-Ser-Trp-His-Arg-Pro-Asp-Lys-Cys-Cys-Leu-Gly-Tyr-Gln-Lys-Arg-Pro-Leu-Pro
-
Sequence Shortening
LGASWHRPDKCCLGYQKRPLP
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
vMIP-II (1-21) Related Classifications
HY-P4109 Related Classifications
Powered by Bioz