1. Signaling Pathways
  2. GPCR/G Protein
    Immunology/Inflammation
  3. CXCR
  4. CXCR4 Inhibitors

CXCR4 Inhibitors

CXCR

CXCR1

CXCR2

CXCR3

CXCR4

CXCR7

CX3CR1

CXCR8

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform CXCR4 together.

Please try each isoform separately.

CXCR4 Specific Inhibitors, Agonists & Antagonists
Product Name CXCR4 CXCR4 Selectivity Purity
Plerixafor
125I-CXCL12-CXCR4, IC50: 44 nM
Selective Antagonist >98.0%
Plerixafor octahydrochloride
125I-CXCL12-CXCR4, IC50: 44 nM
Selective Antagonist >98.0%
USL311
CXCR4
Selective Antagonist 99.97%
LY2510924
SDF-1α-CXCR4, IC50: 79.7 pM
SDF-1α-CXCR4, Ki: 49.5 pM
Selective Inhibitor 99.91%
Mavorixafor trihydrochloride
125I-SDF-CXCR4, IC50: 13 nM
Selective Antagonist 99.14%
Motixafortide
CXCR4, IC50: ∼1 nM
Selective Antagonist 99.19%
IT1t dihydrochloride
CXCL12/CXCR4, IC50: 2.1 nM
Selective Antagonist 98.09%
MSX-122
CXCR4/CXCL12, IC50: ∼10 nM
Selective Antagonist 98.29%
Burixafor hydrobromide
CXCR4
Selective Antagonist >98.0%
Mavorixafor
125I-SDF-CXCR4, IC50: 13 nM
Selective Antagonist
IT1t
CXCL12/CXCR4, IC50: 2.1 nM
Selective Antagonist
ALX 40-4C Trifluoroacetate
SDF-1-CXCR4, Ki: 1 μM
Selective Inhibitor 98.15%
ALX 40-4C
SDF-1-CXCR4, Ki: 1 μM
Selective Inhibitor
ATI-2341
CXCR4, EC50: 194 nM (in CCRF-CEM cells)
Selective Agonist
Baohuoside I
CXCR4
Pan Inhibitor 99.70%