265650-93-9
Chemical Structure
vMIP-II (1-21)
Synonym(s): NT21MP; V1 peptide
- CAS No.: 265650-93-9
- Formula:C108H169N33O27S
- Molecular Weight:2425.84
IUPAC Name: (E)-1,3-dimethoxy-5-(4-((3-methylbut-2-en-1-yl)oxy)styryl)benzene
SMILES: O=C(N1[C@@H](CCC1)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CS)C(N[C@@H](CS)C(N[C@@H](CC(C)C)C(NCC(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](CC(C)C)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)=O)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)NC([C@H](CC5=CN=CN5)NC([C@@H](NC([C@H](CO)NC([C@H](C)NC(CNC([C@@H](N)CC(C)C)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O
Biological Activity: vMIP-II (1-21) (NT21MP) is an inhibitor of CXCR4. vMIP-II (1-21) interacts broadly with CC and CXC chemokine receptors. vMIP-II (1-21) inhibits CXCR4 by competing with 125I-SDF-1R for binding sites (IC50=190 nM)[1].
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vMIP-II (1-21) | vMIP-II (1-21) (NT21MP) is an inhibitor of CXCR4. vMIP-II (1-21) interacts broadly with CC and CXC chemokine receptors. vMIP-II (1-21) inhibits CXCR4 by competing with 125I-SDF-1R for binding sites (IC50=190 nM). | |||||||||||||||||||||
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Keywords
