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  4. Valylhistidine

Valylhistidine is a dipeptide composed of valine and histidine (Val-His). Valylhistidine can form a dipeptide complex with Cu (II) that mimics superoxide dismutase but lacks activity.

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Custom Peptide Synthesis

Valylhistidine

Valylhistidine Chemical Structure

CAS No. : 13589-07-6

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Based on 1 publication(s) in Google Scholar

Valylhistidine Related Antibodies

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Description

Valylhistidine is a dipeptide composed of valine and histidine (Val-His). Valylhistidine can form a dipeptide complex with Cu (II) that mimics superoxide dismutase but lacks activity[1].

In Vitro

Valylhistidine does not catalyze the dismutation of superoxide ion (O2−).Valylhistidine forms a copper(II) complex (Val-His-Cu2+) that acts as a tridentate ligand with three nitrogen atoms bound to the copper ion[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Valylhistidine Related Antibodies
Molecular Weight

254.29

Formula

C11H18N4O3
CAS No.
Appearance

Powder

Color

White to off-white

Sequence

H-Val-His-OH
Sequence Shortening

VH
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (196.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9325 mL 19.6626 mL 39.3252 mL
5 mM 0.7865 mL 3.9325 mL 7.8650 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9325 mL 19.6626 mL 39.3252 mL 98.3130 mL
5 mM 0.7865 mL 3.9325 mL 7.8650 mL 19.6626 mL
10 mM 0.3933 mL 1.9663 mL 3.9325 mL 9.8313 mL
15 mM 0.2622 mL 1.3108 mL 2.6217 mL 6.5542 mL
20 mM 0.1966 mL 0.9831 mL 1.9663 mL 4.9156 mL
25 mM 0.1573 mL 0.7865 mL 1.5730 mL 3.9325 mL
30 mM 0.1311 mL 0.6554 mL 1.3108 mL 3.2771 mL
40 mM 0.0983 mL 0.4916 mL 0.9831 mL 2.4578 mL
50 mM 0.0787 mL 0.3933 mL 0.7865 mL 1.9663 mL
60 mM 0.0655 mL 0.3277 mL 0.6554 mL 1.6385 mL
80 mM 0.0492 mL 0.2458 mL 0.4916 mL 1.2289 mL
100 mM 0.0393 mL 0.1966 mL 0.3933 mL 0.9831 mL
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Valylhistidine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Valylhistidine13589-07-6Biochemical Assay Reagentshistidine-containing dipeptidetridentate ligandnitrogen atomscopper ionsuperoxide ioncopper(II) complexInhibitorinhibitorinhibit

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