Carbonic anhydrase inhibitor 14
Carbonic anhydrase inhibitor 14 (Compound 8b) is a carbonic anhydrase (CA) inhibitor with Ki values of 1203, 99.7, 9.4 and 27.7 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. Carbonic anhydrase inhibitor 14 can also inhibit CDK2 with an IC50 of 20.3 μM. Carbonic anhydrase inhibitor 14 shows antitumor activity.
For research use only. We do not sell to patients.
- CAS No.: 2410402-75-2
- Formula: C18H17N7O2S
- Molecular Weight:395.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CDK2 20.3 μM (IC50) |
hCA XII 27.7 nM (Ki) |
hCA IX 9.4 nM (Ki) |
hCA II 99.7 nM (Ki) |
hCA I 1203 nM (Ki) |
Chemical Information
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CAS No. 2410402-75-2
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Molecular Weight 395.44
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Formula C18H17N7O2S
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SMILES
O=S(C1=CC=C(/N=N/C2=C(NC(C3=CC=C(C)C=C3)=C4)N4N=C2N)C=C1)(N)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Carbonic anhydrase inhibitor 14 Related Classifications
HY-150570 Related Classifications
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