2410402-75-2
Chemical Structure
Carbonic anhydrase inhibitor 14
- CAS No.: 2410402-75-2
- Formula:C18H17N7O2S
- Molecular Weight:395.44
IUPAC Name: (E)-4-((6-amino-2-(p-tolyl)-1H-imidazo[1,2-b]pyrazol-7-yl)diazenyl)benzenesulfonamide
InChIKey: AKCOMXHKFLHYDN-GHVJWSGMSA-N
SMILES: O=S(C1=CC=C(/N=N/C2=C(NC(C3=CC=C(C)C=C3)=C4)N4N=C2N)C=C1)(N)=O
Biological Activity: Carbonic anhydrase inhibitor 14 (Compound 8b) is a carbonic anhydrase (CA) inhibitor with Ki values of 1203, 99.7, 9.4 and 27.7 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. Carbonic anhydrase inhibitor 14 can also inhibit CDK2 with an IC50 of 20.3 μM. Carbonic anhydrase inhibitor 14 shows antitumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Carbonic anhydrase inhibitor 14 | Carbonic anhydrase inhibitor 14 (Compound 8b) is a carbonic anhydrase (CA) inhibitor with Ki values of 1203, 99.7, 9.4 and 27.7 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. Carbonic anhydrase inhibitor 14 can also inhibit CDK2 with an IC50 of 20.3 μM. Carbonic anhydrase inhibitor 14 shows antitumor activity. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
