Angiotensin II 5-valine
Based on 1 Customer Validation
Angiotensin II 5-valine is an agonist of angiotensin receptor.
For research use only. We do not sell to patients.
- Purity: 99.35%
- CAS No.: 58-49-1
- Formula: C49H69N13O12
- Molecular Weight:1032.15
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Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All Angiotensin Receptor Isoforms
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Biological Activity
Angiotensin receptor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 58-49-1
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Appearance Solid
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Molecular Weight 1032.15
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Formula C49H69N13O12
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Color White to off-white
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Synonyms
Valine angiotensin II; 5-L-Valine angiotensin II
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Sequence
Asp-Arg-Val-Tyr-Val-His-Pro-Phe
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Sequence Shortening
DRVYVHPF
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H2O : 100 mg/mL (96.89 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 33.33 mg/mL (32.29 mM); Clear solution; Need ultrasonic
Protocol
Rats[1]
Male Sprague Dawley rats are uninephrectomized and divided into three groups: control (n=6), Angiotensin II 5-valine (exogenous form) infused (n=8), and Angiotensin II 5-valine infused rats treat with losartan (n=8). Angiotensin II 5-valine, which has the same biological and immunoreactive properties as endogenous ANG II, was infused at 40 ng/min via an osmotic minipump implant subcutaneously[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.9689 mL | 4.8443 mL | 9.6885 mL | 24.2213 mL |
| 5 mM | 0.1938 mL | 0.9689 mL | 1.9377 mL | 4.8443 mL | |
| 10 mM | 0.0969 mL | 0.4844 mL | 0.9689 mL | 2.4221 mL | |
| 15 mM | 0.0646 mL | 0.3230 mL | 0.6459 mL | 1.6148 mL | |
| 20 mM | 0.0484 mL | 0.2422 mL | 0.4844 mL | 1.2111 mL | |
| 25 mM | 0.0388 mL | 0.1938 mL | 0.3875 mL | 0.9689 mL | |
| 30 mM | 0.0323 mL | 0.1615 mL | 0.3230 mL | 0.8074 mL | |
| 40 mM | 0.0242 mL | 0.1211 mL | 0.2422 mL | 0.6055 mL | |
| 50 mM | 0.0194 mL | 0.0969 mL | 0.1938 mL | 0.4844 mL | |
| 60 mM | 0.0161 mL | 0.0807 mL | 0.1615 mL | 0.4037 mL | |
| 80 mM | 0.0121 mL | 0.0606 mL | 0.1211 mL | 0.3028 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.