1. Epigenetics
    TGF-beta/Smad
  2. PKC
  3. Myelin Basic Protein TFA

Myelin Basic Protein TFA (Synonyms: MHP4-14 TFA)

Cat. No.: HY-P1821A Purity: 95.02%
Handling Instructions

Myelin Basic Protein (MHP4-14) TFA, a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein TFA is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts.

For research use only. We do not sell to patients.

Myelin Basic Protein TFA Chemical Structure

Myelin Basic Protein TFA Chemical Structure

Size Price Stock Quantity
5 mg USD 100 In-stock
Estimated Time of Arrival: December 31
10 mg USD 150 In-stock
Estimated Time of Arrival: December 31
50 mg USD 450 In-stock
Estimated Time of Arrival: December 31
100 mg USD 720 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Myelin Basic Protein TFA:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Myelin Basic Protein TFA

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Myelin Basic Protein (MHP4-14) TFA, a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein TFA is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts[1][2].

In Vitro

Once MBP4-14 is phosphorylated, it is not dephosphorylated by okadaic acid-sensitive phosphatases (protein phosphatases 1, 2A and 3) or other protein phosphatases such as calcineurin and/or PP 2C present in hippocampal homogenates. Therefore, MBP4-14 can be used for PKC assay in crude extracts of neural tissue[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1504.61

Formula

C₆₂H₁₀₄F₃N₂₁O₁₉

Sequence Shortening

QKRPSQRSKYL

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (66.46 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6646 mL 3.3231 mL 6.6462 mL
5 mM 0.1329 mL 0.6646 mL 1.3292 mL
10 mM 0.0665 mL 0.3323 mL 0.6646 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
Myelin Basic Protein TFA
Cat. No.:
HY-P1821A
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