1. Autophagy Neuronal Signaling
  2. Autophagy CaMK
  3. Calmodulin-Dependent Protein Kinase II(290-309) acetate

Calmodulin-Dependent Protein Kinase II(290-309) acetate 

Cat. No.: HY-P1479A Purity: 98.45%
COA Handling Instructions

Calmodulin-Dependent Protein Kinase II (290-309) acetate is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II.

For research use only. We do not sell to patients.

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Calmodulin-Dependent Protein Kinase II(290-309) acetate Chemical Structure

Calmodulin-Dependent Protein Kinase II(290-309) acetate Chemical Structure

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5 mg USD 580 In-stock
10 mg USD 800 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Calmodulin-Dependent Protein Kinase II (290-309) acetate is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II[1].

IC50 & Target

IC50: 52 nM (calmodulin-dependent protein kinase II)[1].

In Vitro

Peptide 290 to 309 is found to be a potent calmodulin antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase. Neither truncation from the amino terminus (peptide 296-309) nor extension in the carboxyl-terminal direction (peptide 294-319) markedly affects calmodulin binding, whereas shortening the peptide from the carboxyl terminus (peptide 290-302) or from both ends (peptide 295-304) results in the elimination of this activity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

2333.88

Formula

C105H189N31O26S

Appearance

Solid

Color

White to off-white

Sequence Shortening

LKKFNARRKLKGAILTTMLA

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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Calmodulin-Dependent Protein Kinase II(290-309) acetate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Calmodulin-Dependent Protein Kinase II(290-309) acetate
Cat. No.:
HY-P1479A
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