1. Immunology/Inflammation
  2. COX
  3. Tazofelone

Tazofelone (Synonyms: LY 213829)

Cat. No.: HY-137789 Purity: 98.89%
Handling Instructions

Tazofelone (LY 213829) is a cyclooxygenase-II (COX-II) inhibitor. Tazofelone transform into sulfoxide and quinol metabolites is primarily mediated by CYP3A. Tazofelone can be used for the research of inflammatory bowel disease.

For research use only. We do not sell to patients.

Tazofelone Chemical Structure

Tazofelone Chemical Structure

CAS No. : 107902-67-0

Size Price Stock Quantity
5 mg USD 320 In-stock
Estimated Time of Arrival: December 31
10 mg USD 480 In-stock
Estimated Time of Arrival: December 31
25 mg USD 960 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1440 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Description

Tazofelone (LY 213829) is a cyclooxygenase-II (COX-II) inhibitor. Tazofelone transform into sulfoxide and quinol metabolites is primarily mediated by CYP3A. Tazofelone can be used for the research of inflammatory bowel disease[1][2].

Molecular Weight

321.48

Formula

C18H27NO2S

CAS No.
SMILES

O=C1NCSC1CC2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (311.06 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1106 mL 15.5531 mL 31.1061 mL
5 mM 0.6221 mL 3.1106 mL 6.2212 mL
10 mM 0.3111 mL 1.5553 mL 3.1106 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.78 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.78 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
Tazofelone
Cat. No.:
HY-137789
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