1. Recombinant Proteins
  2. Immune Checkpoint Proteins
  3. Butyrophilins
  4. BTNL2
  5. BTNL2 Protein, Human (Cell-Free, His)

BTNL2 Protein, Human (Cell-Free, His)

Cat. No.: HY-P702225
Handling Instructions

BTNL2 protein acts as a negative regulator of T-cell proliferation, crucially modulating the immune response. Its regulatory activity helps control T-cell division, contributing to immune reaction fine-tuning. This negative regulatory function underscores BTNL2's importance in maintaining immune homeostasis, preventing excessive T-cell proliferation, and highlighting its potential significance in immune-related disorders. BTNL2 Protein, Human (Cell-Free, His) is the recombinant human-derived BTNL2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of BTNL2 Protein, Human (Cell-Free, His) is 455 a.a., with molecular weight of 53.3 kDa.

For research use only. We do not sell to patients.

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Description

BTNL2 protein acts as a negative regulator of T-cell proliferation, crucially modulating the immune response. Its regulatory activity helps control T-cell division, contributing to immune reaction fine-tuning. This negative regulatory function underscores BTNL2's importance in maintaining immune homeostasis, preventing excessive T-cell proliferation, and highlighting its potential significance in immune-related disorders. BTNL2 Protein, Human (Cell-Free, His) is the recombinant human-derived BTNL2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of BTNL2 Protein, Human (Cell-Free, His) is 455 a.a., with molecular weight of 53.3 kDa.

Background

BTNL2 protein functions as a negative regulator of T-cell proliferation, playing a crucial role in modulating the immune response. Through its regulatory activity, BTNL2 helps control the rate of T-cell division, contributing to the fine-tuning of immune reactions. This negative regulatory function underscores the importance of BTNL2 in maintaining immune homeostasis and preventing excessive T-cell proliferation, which could lead to uncontrolled immune responses. The precise mechanisms through which BTNL2 exerts its inhibitory effects on T-cell proliferation make it a key player in immune system modulation and highlight its potential significance in immune-related disorders.

Species

Human

Source

E. coli Cell-free

Tag

N-10*His

Accession

Q9UIR0 (M1-W455)

Gene ID

56244

Molecular Construction
N-term
10*His
BTNL2 (M1-W455)
Accession # Q9UIR0
C-term
Synonyms
Butyrophilin-like protein 2; BTL-II
AA Sequence

MVDFPGYNLSGAVASFLFILLTMKQSEDFRVIGPAHPILAGVGEDALLTCQLLPKRTTMHVEVRWYRSEPSTPVFVHRDGVEVTEMQMEEYRGWVEWIENGIAKGNVALKIHNIQPSDNGQYWCHFQDGNYCGETSLLLKVAGLGSAPSIHMEGPGESGVQLVCTARGWFPEPQVYWEDIRGEKLLAVSEHRIQDKDGLFYAEATLVVRNASAESVSCLVHNPVLTEEKGSVISLPEKLQTELASLKVNGPSQPILVRVGEDIQLTCYLSPKANAQSMEVRWDRSHRYPAVHVYMDGDHVAGEQMAEYRGRTVLVSDAIDEGRLTLQILSARPSDDGQYRCLFEKDDVYQEASLDLKVVSLGSSPLITVEGQEDGEMQPMCSSDGWFPQPHVPWRDMEGKTIPSSSQALTQGSHGLFHVQTLLRVTNISAVDVTCSISIPFLGEEKIATFSLSGW

Molecular Weight

53.3 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

BTNL2 Protein, Human (Cell-Free, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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BTNL2 Protein, Human (Cell-Free, His)
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HY-P702225
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