UPK2 Protein, Human (HEK293, His)

UPK2 is a key component of the asymmetric unit membrane (AUM), a specialized biofilm made by terminally differentiated urothelial cells. Its presence suggests a potentially critical role in the complex regulation of AUM assembly. UPK2 Protein, Human (HEK293, His) is the recombinant human-derived UPK2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of UPK2 Protein, Human (HEK293, His) is 130 a.a., with molecular weight of ~27.0 kDa.

The UPK2 protein serves as a crucial constituent of the asymmetric unit membrane (AUM), a specialized biomembrane intricately developed by fully differentiated urothelial cells. Its potential involvement in regulating AUM assembly underscores its significance in maintaining the structural integrity and specialized functions of urothelial cells. Through its interaction with uroplakin-1a (UPK1A), UPK2 forms part of a molecular network that likely contributes to the unique properties of the AUM. This association highlights the intricate interplay between UPK2 and UPK1A, shedding light on their cooperative roles in the intricate biology of terminally differentiated urothelial cells (By similarity).

Human

HEK293

C-6*His

O00526 (D26-G155)

7379  [NCBI]

DFNISSLSGLLSPALTESLLVALPPCHLTGGNATLMVRRANDSKVVTSSFVVPPCRGRRELVSVVDSGAGFTVTRLSAYQVTNLVPGTKFYISYLVKKGTATESSREIPMSTLPRRNMESIGLGMARTGG

Approximately 27.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.