2. Signaling Pathways
  3. Anti-infection
  4. TMV

TMV

Tobacco mosaic virus

Tobacco mosaic virus (TMV) is named for one of the first plants in which it was found in the 1886. TMV can infect well over 350 different species of plants, many of which are favorites in home gardens such as tomatoes and potatoes. However TMV exclusively infects plants and is completely harmless for mammals. The rod-shaped virus particles (virions) of TMV measure about 300 nm x 15 nm. A single TMV particle is composed of 2,130 copies of the coat protein (CP) that envelope the RNA molecule of about 6,400 nucleotides. This single-stranded RNA encodes four genes: two replicase-associated proteins that are directly translated from the TMV RNA, and the movement protein and a coat protein that are translated from subgenomic RNAs. TMV is the textbook example for self-assembly. The assembly of the CPs (with or without RNA) to viruslike tubes is becoming an attractive way for nanoscale construction.

TMV Related Products (13):

Cat. No. Product Name Effect Purity
  • HY-N4210
    Yadanziolide A
    		99.41%
    Yadanziolide A, isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects.
  • HY-N7532
    Yadanzioside I
    Yadanzioside I is a potent anti-tobacco mosaic virus (TMV) quassinoid with an IC50 of 4.22 μM.
  • HY-Y0507
    DL-Serine
    		≥98.0%
    DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV).
  • HY-148569
    TMV-IN-3
    		Inhibitor
    TMV-IN-3, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-3 has antiviral activity against TMV with an EC50 value of 120.3 μg/mL. TMV-IN-3 can be used for the research of infection, inflammation and tumor.
  • HY-148568
    TMV-IN-2
    		Inhibitor
    TMV-IN-2, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-2 has antiviral activity against TMV with an EC50 value of 89.9 μg/mL. TMV-IN-2 can be used for the research of infection, inflammation and tumor.
  • HY-155045
    TMV-IN-6
    		Inhibitor
    TMV-IN-6 (Compound 4g) is a novel antiviral and fungicidal agent. TMV-IN-6 inhibits virus assembly by binding totobacco mosaic virus (TMV) CP and interfere with the assembly process of TMV CP and RNA.
  • HY-N10110
    (±)-Phrymarolin II
    (±)-Phrymarolin II is a promising new class of plant virus (tobacco mosaic virus) inhibitors.
  • HY-145324
    Antiviral agent 14
    Antiviral agent 14 is an antiviral agent against the tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV). The EC50 values of Antiviral agent 14 against TMV and CMV with EC50 values of 135.5 μg/mL and 178.6 μg/mL, respectively.
  • HY-Y0507S
    DL-Serine-2,3,3-d3
    		98.39%
    DL-Serine-2,3,3-d3 is the deuterium labeled DL-Serine. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV)[1].
  • HY-N8024
    Rubinaphthin A
    Rubinaphthin A is a naphthohydroquinone that can be found in the roots of Rubia yunnanensis. Rubinaphthin A exhibits inhibitory activity against tobacco mosaic virus (TMV).
  • HY-152259
    TMV-IN-4
    		Inhibitor
    TMV-IN-4 (compound 3) is a tobacco mosaic virus (TMV) inhibitor that effectively induces resistance and enhances plant tolerance to TMV infection by interacting with TMV helicase. TMV-IN-4 enhances peroxidase and superoxide dismutase activity, thereby increasing resistance to TMV in tobacco.
  • HY-N7194
    Yadanzioside L
    Yadanzioside L is a quassinoid and shows anti-tobacco mosaic virus (TMV) activity (IC50=4.86 μM).
  • HY-148567
    TMV-IN-1
    		Inhibitor
    TMV-IN-1, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-1 has good therapeutic activity and protective activity against TMV with EC50 values of 70.7 μg/mL and 60.8 μg/mL, respectively. TMV-IN-1 can be used for the research of infection, inflammation and tumor.