19337-97-4
19337-97-4
Chemical Structure
trans-3-(3-Pyridyl)acrylic acid
- CAS No.: 19337-97-4
- Formula:C8H7NO2
- Molecular Weight:149.15
IUPAC Name: (E)-3-(pyridin-3-yl)acrylic acid
InChIKey: VUVORVXMOLQFMO-ONEGZZNKSA-N
SMILES: O=C(/C=C/C1=CC=CN=C1)O
Biological Activity: trans-3-(3-Pyridyl) acrylic acid is an unsaturated carboxylic acid and synthetic building block, which serves as a synthetic precursor of 3-(3-pyridyl) propanoic acid. trans-3-(3-Pyridyl) acrylic acid can be used to prepare dual mutant IDH1/NAMPT inhibitors and PGE2 antagonist analogs. In addition, trans-3-(3-Pyridyl) acrylic acid exhibits antiviral activity against tobacco mosaic virus (TMV)[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
trans-3-(3-Pyridyl)acrylic acid | 99.90% | trans-3-(3-Pyridyl) acrylic acid is an unsaturated carboxylic acid and synthetic building block, which serves as a synthetic precursor of 3-(3-pyridyl) propanoic acid. trans-3-(3-Pyridyl) acrylic acid can be used to prepare dual mutant IDH1/NAMPT inhibitors and PGE2 antagonist analogs. In addition, trans-3-(3-Pyridyl) acrylic acid exhibits antiviral activity against tobacco mosaic virus (TMV). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Wu M, et al. Discovery and SARs of trans-3-aryl acrylic acids and their analogs as novel anti-tobacco mosaic virus (TMV) agents. PLoS One. 2013;8(2):e56475. [Content Brief]
- [2]. Wen F, et al. Discovery of Novel Dual Inhibitors Targeting Mutant IDH1 and NAMPT for the Treatment of Glioma with IDH1Mutation. J Med Chem. 2024;67(11):8667-8692. [Content Brief]
- [3]. Hallinan EA, et al. N-substituted dibenzoxazepines as analgesic PGE2 antagonists. J Med Chem. 1993;36(22):3293-3299. [Content Brief]
