145987-74-2
145987-74-2
Chemical Structure
7-Deoxy-trans-dihydronarciclasine
- CAS No.: 145987-74-2
- Formula:C14H15NO6
- Molecular Weight:293.27
InChIKey: KKAHUDOWKGIGAA-IAWGOJCDSA-N
SMILES: O=C1C2=CC(OCO3)=C3C=C2[C@]4([H])[C@@]([C@@H]([C@@H]([C@H](C4)O)O)O)([H])N1
Biological Activity: 7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC50: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice[1][2][3].
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7-Deoxy-trans-dihydronarciclasine | 7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC50: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice. | |||||||||||||||||||||
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References
- [1]. Wang YH, et al. Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase. J Nat Prod. 2007 Sep;70(9):1458-61. [Content Brief]
- [2]. Zhao D, et al. 7-Deoxy-trans-dihydronarciclasine Isolated from Lycoris chejuensis Inhibits Neuroinflammation in Experimental Models. J Agric Food Chem. 2019 Sep 4;67(35):9796-9804. [Content Brief]
Keywords
