CK2 alpha/CSNK2A1 Protein, Mouse (sf9)
The CK2 α/CSNK2A1 protein is a constitutively active kinase that phosphorylates substrates and regulates cell cycle, apoptosis, transcription, and viral infection. CK2 α/CSNK2A1 also regulates the cellular clock, Wnt signaling, modulates extracellular proteins, and plays a role in viral infection. CK2 alpha/CSNK2A1 Protein, Mouse (sf9) is the recombinant mouse-derived CK2 alpha/CSNK2A1 protein, expressed by Sf9 insect cells, with tag free.
- Species: Mouse
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
The CK2 α/CSNK2A1 protein is a constitutively active kinase that phosphorylates substrates and regulates cell cycle, apoptosis, transcription, and viral infection. CK2 α/CSNK2A1 also regulates the cellular clock, Wnt signaling, modulates extracellular proteins, and plays a role in viral infection. CK2 alpha/CSNK2A1 Protein, Mouse (sf9) is the recombinant mouse-derived CK2 alpha/CSNK2A1 protein, expressed by Sf9 insect cells, with tag free.
The catalytic subunit of CK2 alpha/CSNK2A1 protein is an integral component of a constitutively active serine/threonine-protein kinase complex, exhibiting the ability to phosphorylate numerous substrates rich in acidic residues C-terminal to the phosphorylated serine or threonine. This multifaceted kinase regulates diverse cellular processes, including cell cycle progression, apoptosis, transcription, and viral infection. Operating as a regulatory hub, CK2 alpha/CSNK2A1 integrates signals and orchestrates appropriate cellular responses, such as maintaining the spindle assembly checkpoint during mitosis and facilitating p53/TP53-mediated apoptosis. Additionally, CK2 alpha/CSNK2A1 participates in intricate signaling networks by phosphorylating various transcription factors, apoptotic regulators, and extracellular proteins. Its impact extends to the circadian clock function and viral life cycles, emphasizing its pivotal role in cellular homeostasis and response to external stimuli.
Technical Parameters
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Species Mouse
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Source Sf9 insect cells
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Tag Tag Free
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Accession
Q60737 (N-G&P, M1-Q391)
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Molecular Construction
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N-term
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Gly-Pro
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CSNK2A1 (M1-Q391)
Accession # Q60737 -
C-term
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Protein Length
Full Length
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Synonyms
CSNK2A1; Casein Kinase II Alpha 1 Polypeptide Pseudogene; Casein Kinase 2 Alpha 1; Non-Specific Serine/Threonine Protein Kinase; Casein Kinase II Subunit Alpha; Casein Kinase II Alpha 1 Subunit; Cka1; CK2 Catalytic Subunit Alpha; Cka2; Protein Kinase CK2;
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Predicted Molecular Mass
45.3 kDa
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Molecular Weight
Approximately 40 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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