Csnk2a1 - casein kinase 2, alpha 1 polypeptide Gene
Also Known as CK2; Csnk2a1-rs4
Species: Mus musculus
Summary
Casein Kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, Apoptosis, and circadian rhythms. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Feb 2014]
Csnk2a1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_007788.3 | NP_031814.2 | casein kinase II subunit alpha |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables beta-catenin binding |
IDA
IDA: Inferred from direct assay
|
12432063 | MGI |
| enables kinase activity |
IDA
IDA: Inferred from direct assay
|
15284227 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
12432063 | MGI |
| enables protein phosphatase regulator activity |
IDA
IDA: Inferred from direct assay
|
15284227 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within protein autophosphorylation |
IDA
IDA: Inferred from direct assay
|
18191828 | MGI |
| acts upstream of or within protein phosphorylation |
IDA
IDA: Inferred from direct assay
|
12432063 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
casein kinase II subunit alpha |
|
|
Recombinant Csnk2a1 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P76825 | CK2 alpha/CSNK2A1 Protein, Mouse (sf9) | Q60737 (N-G&P, M1-Q391) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P76826 | CK2 alpha/CSNK2A1 Protein, Mouse (Active, sf9, His-GST) | Q60737 (M1-Q391) | ≥ 85%, as determined by reducing SDS-PAGE. |