CSNK2-IN-1
CSNK2-IN-1 is a potent and selective CSNK2 inhibitor with IC50 of 1.7 nM and 0.66 nM for CSNK2A1 and CSNK2A2, respectively. CSNK2-IN-1 has antiviral activity against beta-coronaviruses such as SARS-CoV-2 and MHV. CSNK2-IN-1 has good solubility, metabolic stability, and low cytotoxicity, but its plasma concentration in vivo decreases rapidly and is insufficient to achieve pharmacological effects. CSNK2-IN-1 can be used in the research of antiviral drug development.
For research use only. We do not sell to patients.
- CAS No.: 3105428-74-5
- Formula: C22H25N11
- Molecular Weight:443.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 3105428-74-5
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Molecular Weight 443.51
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Formula C22H25N11
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SMILES
N#CC1=C2N=C(C=C(N2N=C1)NC3CC3)NC4=CC=C(C(N5C=NN=C5)=C4)N(CC)CCN
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)