1. Neuronal Signaling
  2. CaMK

Syntide 2 

Cat. No.: HY-P0271
Handling Instructions

Syntide 2 is recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII) with a Ki of 12 μM. Sequence: Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Syntide 2 Chemical Structure

Syntide 2 Chemical Structure

CAS No. : 108334-68-5

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1 mg USD 84 Get quote
5 mg USD 288 Get quote
10 mg USD 456 Get quote

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Syntide 2 is recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII) with a Ki of 12 μM. Sequence: Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys.

IC50 & Target

Km: 12 μM (CaMKII)[1]

In Vitro

The sequence of syntide-2 (pro-leu-ala-arg-thr-leu-ser-val-ala-gly-leu-pro-gly-lys-lys) is homologous to phosphorylation site 2 in glycogen synthase. The relative Vmax/Km ratios of the known Ca2+-dependent protein kinases for syntide-2 are determined to be as follows: protein kinase II, 100; protein kinase C, 22; phosphorylase kinase, 2; myosin light chain kinase, 0.005[1].

Solvent & Solubility
In Vitro: 

10 mM in H2O

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6632 mL 3.3160 mL 6.6321 mL
5 mM 0.1326 mL 0.6632 mL 1.3264 mL
10 mM 0.0663 mL 0.3316 mL 0.6632 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

1507.82

Formula

C₆₈H₁₂₂N₂₀O₁₈

CAS No.

108334-68-5

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Syntide 2
Cat. No.:
HY-P0271
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Syntide 2

Cat. No.: HY-P0271