1. Cell Cycle/DNA Damage Anti-infection
  2. Topoisomerase Antibiotic Bacterial
  3. CP-67015

CP-67015, a quinolone antibiotic, is a potent topoisomerase II inhibitor. CP-67015 is a positive direct-acting mutagen in mammalian cells with both gene and chromosomal level effects.

For research use only. We do not sell to patients.

CP-67015 Chemical Structure

CP-67015 Chemical Structure

CAS No. : 100325-51-7

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Description

CP-67015, a quinolone antibiotic, is a potent topoisomerase II inhibitor. CP-67015 is a positive direct-acting mutagen in mammalian cells with both gene and chromosomal level effects[1].

IC50 & Target[1]

Quinolone

 

Topoisomerase II

 

In Vitro

CP-67015 (10-100 μg/mL; 12-36 h) produces a drastic increase in chromosome damage in human lymphocytes and in CHO cells[1].
CP-67015 inhibits supercoiling activity of prokaryotic DNA gyrase, with 100% inhibition at the concentration of 4.0 μg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

CP-67015 (a single dose 1000 mg/kg or 500 mg/kg/day for 5 days; i.p.) induces chromosome damage in male CD-1 mice in mouse bone marrow cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

330.29

Formula

C17H12F2N2O3

CAS No.
SMILES

O=C(C1=CN(CC)C2=C(C=C(F)C(C3=CC=NC=C3)=C2F)C1=O)O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CP-67015
Cat. No.:
HY-109855
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